Lesion of the Cerebellar Noradrenergic Innervation Enhances the Harmaline-Induced Tremor in Rats

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Riluzole Ameliorates Harmaline-Induced Tremor in Rat

Introduction: Excessive olivo-cerebellar burst-firing occurs during harmaline-induced tremor. We hypothesized that antiglutamatergic agents would suppress harmaline tremor. From this point of view, the aim of current study was to investigate the effects of riluzole on harmaline-induced tremor in rat. Material and Methods: Four groups of Wistar rats weighing 80–100 g were injected with harmaline...

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Riluzole Ameliorates Harmaline-induced Tremor in Rat

INTRODUCTION Excessive olivo-cerebellar burst-firing occurs during harmaline-induced tremor. We hypothesized that antiglutamatergic agents would suppress harmaline tremor. From this point of view, the aim of the present study was to investigate the effects of riluzole on harmaline-induced tremor in rat. METHODS Four groups of Wistar rats weighing 80-100 g were injected with harmaline (30 mg/ ...

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The effect of memantine in harmaline-induced tremor and neurodegeneration.

Essential tremor (ET) is one of the most common and most disabling movement disorders among adults. The drug treatment of ET remains unsatisfactory. Additional therapies are required for patients with inadequate response or intolerable side effects. The current study aims to investigate the anti-tremogenic and neuroprotective effects of memantine (NMDA receptor antagonist) on the harmaline mode...

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riluzole ameliorates harmaline-induced tremor in rat

introduction: excessive olivo-cerebellar burst-firing occurs during harmaline-induced tremor. we hypothesized that antiglutamatergic agents would suppress harmaline tremor. from this point of view, the aim of current study was to investigate the effects of riluzole on harmaline-induced tremor in rat. material and methods: four groups of wistar rats weighing 80–100 g were injected with harmaline...

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ژورنال

عنوان ژورنال: The Cerebellum

سال: 2011

ISSN: 1473-4222,1473-4230

DOI: 10.1007/s12311-011-0250-9